Yup. I've been on spironolactone (50mg/day) for the last two years and it has effectively helped me to manage my stage 2 HS by almost eliminating my breakouts. I'll still occasionally get a cystic lesion, but they are smaller and fewer than the ones I would develop pre-spiro. And I've had maybe one or two larger cystic legions creep up on me since then, but I treat them with topical betamethasone my germ prescribed for me to use on an as-needed basis while taking the spiro, and it's pretty effective. The new lesions (the few I've sprouted despite the spiro) tend to last mere days or a few weeks vs. the months the previous ones would last.