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Real members of myHSteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

My dermatologist just prescribed Spironolactone for my HS. I’m a little nervous about taking it after reading the side effects.

A myHSteam Member asked a question 💭
July 9
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Reactions
A myHSteam Member

Keep us updated on the Spironolactone, it was a game changer for me on stopping the flare ups 💚

July 12
A myHSteam Member

I’m hoping it helps with the flare ups. I use to only get them under my arms but now I get them on my butt and some are close to the groin. I was already taking birth control so I hope that helps with some of the side effects as well.

July 11
A myHSteam Member

I was put on 100mg of Spironolactone daily in 2025. My labs have been excellent, even though I take a daily vitamin. I do avoid foods with excessive amounts of Potassium which isn't fun because I love some of those. Since being put on the medication, I have had one flare up under my arm and it didn't get nearly as bad as it would previously. Once I was put on it by the ER doctor because she finally recognized my symptoms instead of just treating and streeting me, my tunneled abcesses cleared up and the area under my arm slowly healed. As an added benefit my acne that I have dealt with well into my 40s cleared up. I hardly ever get a pimple or oil bump on my face anymore. It's been a miracle in my life. Now if I could just find a product that hides acne scars on your chin I would be absolutely thrilled. I am so self conscious about those.

July 9
myHSteam

It's completely understandable to feel nervous — starting a new medication can feel like a big step. The good news is that in studies specifically looking at spironolactone for HS, relatively few side effects were actually reported by participants.

That said, it's worth knowing what to watch for. Possible side effects Show Full Answer

It's completely understandable to feel nervous — starting a new medication can feel like a big step. The good news is that in studies specifically looking at spironolactone for HS, relatively few side effects were actually reported by participants.

That said, it's worth knowing what to watch for. Possible side effects include:

- Digestive issues like nausea, vomiting, or diarrhea
- Electrolyte imbalances (higher potassium levels), which can cause shaking, fainting, or light-headedness
- Skin reactions such as rash or hair loss
- Neurological effects like headaches, confusion, or tiredness

Higher doses tend to come with more side effects, so your dermatologist will likely start you on a lower dose. There are also some situations where spironolactone isn't recommended. It's generally not advised for those who are pregnant or breastfeeding. It's also not typically prescribed for men due to the risk of breast enlargement.

People with kidney or liver concerns, or older individuals, should use it with caution since it can put some strain on those organs. On the positive side, studies have shown promising results for women with HS taking spironolactone — including fewer lesions and less pain after several months of use. One small study found that 17 out of 20 women saw improved symptoms after just three months.

It's always okay to go back to your dermatologist with questions or concerns before starting — that's what they're there for!

July 9
A myHSteam Member

I'm sure you will be fine but if you have any side effects let the doctor know. I hope you feel better.

August 6

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