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GLP-1 medications like Ozempic, Wegovy, or Mounjaro. What was your experience? We are seeking more information from the community and hope you'll share your experience.

December 29, 2025
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Answer Summary

Members shared a wide range of experiences using GLP-1 medications like Mounjaro, Wegovy, Ozempic, and Zepbound in relation to their HS... Read more

Members shared a wide range of experiences using GLP-1 medications like Mounjaro, Wegovy, Ozempic, and Zepbound in relation to their HS symptoms. Several members reported meaningful improvement, including fewer flare-ups, less severe lesions, and in some cases near-complete remission, while others noticed little to no change or even a worsening of symptoms. A recurring theme was uncertainty about whether benefits came from the medication itself, improved blood sugar control, weight loss, or healthier eating habits that came along with it.

A myHSteam Member

Yes. I have been on ozembic for a little over a year. Once my a1c leveled out, my HS outbreaks have dramatically decreased.  I no longer need antibiotics  for my HS. It has improved my life greatly. Sent from my T-Mobile 5G Device
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December 29, 2025
A myHSteam Member

I am eating so healthy that I am not getting new breakouts. Areas that have been bad for YEARS are healing. I still have scarring from the healed areas.

December 29, 2025
A myHSteam Member

I took ozempic for over a year and had to stop it because of the GI side effects. I took a 3 month break and started mounjuno. I lost about 40ish pounds with ozempic, but I was taking it for my diabetes. I did notice a decrease in lesions, but they did not stop completely. I get them under my abdominal fold and on the side of my right breast. I have also ragged out some T-shirts and I tuck it under my abdominal fold. Since I started doing that, I have had no yeast and my HS lesions are, when I do get them, much less severe. I hope this helps!!

December 29, 2025
A myHSteam Member

Yes! Up until a few months ago I was on Mounjaro. My HS reduced so much I could wear a tank top for the first time in 2 decades!

Then I started a job where the insurance scoffed at GLP-1's and refused to cover it due to the use of it being for weight loss (nice benefit but I was using it to control my diabetes primarily.

December 29, 2025
A myHSteam Member

I am on Zepbound. My HS is certainly greatly improved but not gone altogether. I get smaller flares and less erupting flares. Bumps appear but go down without bursting most times.

December 29, 2025

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