DISEASE-MODIFYING ANTIRHEUMATIC DRUG (DMARD)
Methotrexate is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat severe cases of psoriasis, rheumatoid arthritis, and some types of cancer. Methotrexate is sometimes prescribed to treat hidradenitis suppurativa (HS). In cases of HS, methotrexate is often prescribed in combination with another medication such as Humira. Methotrexate is sold under brand names including Rheumatrex and Trexall.
Methotrexate is an immunomodulator, or drug that modifies the immune system. Methotrexate is a type of disease-modifying antirheumatic drug (DMARD). Methotrexate is believed to suppress the immune system in several ways, reducing the activity of T cells, B cells, interleukins, and enzymes that play a role in autoimmune attacks.
How do I take it?
Methotrexate is generally prescribed to be taken once or twice each week.
Methotrexate may be taken orally or by intramuscular or intravenous injection.
The FDA-approved label for methotrexate lists common side effects including nausea, vomiting, loss of appetite, and temporary hair loss.
Rare but serious side effects listed for Methotrexate include infections, birth defects, seizures, and damage to liver, lungs, or kidneys.
For more details about this treatment, visit:
Methotrexate — Drugs.com
Hidradenitis Suppurativa: A Review With an Emphasis on Treatment — Consultant 360
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