There are quite a few treatment options for HS, and the right combination really depends on the severity of your condition and your individual needs. Here's a breakdown of the main categories:
Antibiotics
- Topical antibiotics (like clindamycin) help reduce bacteria and inflammation on the skin
- Oral antibiotics (like Show Full Answer
There are quite a few treatment options for HS, and the right combination really depends on the severity of your condition and your individual needs. Here's a breakdown of the main categories:
Antibiotics
- Topical antibiotics (like clindamycin) help reduce bacteria and inflammation on the skin
- Oral antibiotics (like tetracycline or rifampin with clindamycin) target inflammation and bacterial growth from the inside
Hormonal Therapies
- Combined oral contraceptives (birth control pills containing both estrogen and progesterone) help balance hormone levels
- Spironolactone reduces the effects of androgen hormones
- Finasteride lowers levels of a hormone called DHT, which is made from testosterone
Biologics
These target specific parts of the immune system to reduce inflammation. FDA-approved options include:
- Adalimumab (Humira)
- Bimekizumab (Bimzelx)
- Secukinumab (Cosentyx)
Other Medications
- Oral retinoids (like acitretin or isotretinoin) help regulate skin cell turnover
- Corticosteroids (like prednisone) reduce inflammation, usually used short-term during flares
- Metformin may help reduce inflammation, particularly for those with insulin resistance
- NSAIDs (like ibuprofen) can help manage pain and inflammation It's worth noting that a myHSteam member shared that after trying all antibiotics without success, they found relief with a biologic, saying it was "slowly taking effect."
Everyone's HS is different, so working closely with your dermatologist to find the right combination is really important. Don't hesitate to ask about all available options!
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