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Real members of myHSteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Cosentyx Vs Humira?

A myHSteam Member asked a question 💭
Grand Rapids, MI

Currently on Humira and very unhappy with lack of results. Looking at other options

September 23
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A myHSteam Member

Hi Coda, I’ve been on Cosentyx for a few months. No new lesions. The 4 I have are slowly to leak. So not totally gone but, I’m working on it.

September 23
A myHSteam Member

It sounds like you're considering switching from Humira to Cosentyx for treating your hidradenitis suppurativa (HS). Here's a comparison based on my knowledge base:

Cosentyx (Secukinumab)
- Type: Biologic disease-modifying antirheumatic drug (DMARD)
- Mechanism: Inhibits interleukin 17A (IL-17A), a chemical messenger read more

It sounds like you're considering switching from Humira to Cosentyx for treating your hidradenitis suppurativa (HS). Here's a comparison based on my knowledge base:

Cosentyx (Secukinumab)
- Type: Biologic disease-modifying antirheumatic drug (DMARD)
- Mechanism: Inhibits interleukin 17A (IL-17A), a chemical messenger involved in HS inflammation.
- Administration: Subcutaneous injection every four weeks, or every two weeks if needed.
- Common Side Effects: Cold symptoms, upper respiratory tract infections, diarrhea.
- Serious Side Effects: Severe infections, inflammatory bowel disease, hypersensitivity reactions.

Humira (Adalimumab)
- Type: Biologic drug
- Mechanism: Neutralizes tumor necrosis factor alpha (TNF-α), a chemical messenger involved in autoimmune attacks.
- Administration: Subcutaneous injection every week or every other week after an initial loading dose.
- Common Side Effects: Respiratory infections, headache, redness or irritation at injection sites, rash.
- Serious Side Effects: Severe allergic reactions, potentially fatal infections, new or worsening heart failure, lupus-like syndrome, demyelinating disease, increased risk of certain cancers like lymphoma.

Considerations
- Effectiveness: Both drugs are FDA-approved for treating moderate to severe HS, but individual responses can vary.
- Side Effects: Consider the side effect profiles and discuss with your healthcare provider which might be more suitable for you.
- Administration Frequency: Cosentyx is typically administered less frequently than Humira, which might be more convenient.

It's important to consult with your healthcare provider to discuss your specific situation and determine the best treatment option for you.

 This AI-generated response comes from myHSteam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

Cosentyx (Secukinumab) for Hidradenitis suppurativa | myHSteam
Humira (Adalimumab) for Hidradenitis suppurativa | myHSteam
September 23
A myHSteam Member

I started AMJEVITA today. I’ll post how it goes. Taking another shot in two weeks

September 23
A myHSteam Member

@A myHSteam Member im seeing the dermatologist tomorrow, will definitely be bringing up the possibility of a switch

September 23

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