Yes, it is still possible to experience HS flare-ups while taking adalimumab (Humira), even though it is FDA-approved for moderate to severe HS and can be very effective at reducing flares for many people. Research during the COVID-19 pandemic found that people on biologics like adalimumab were much less likely to flare Show Full Answer
Yes, it is still possible to experience HS flare-ups while taking adalimumab (Humira), even though it is FDA-approved for moderate to severe HS and can be very effective at reducing flares for many people. Research during the COVID-19 pandemic found that people on biologics like adalimumab were much less likely to flare after an infection — but "much less likely" doesn't mean flares are impossible. The medication works by calming the immune system, which helps prevent it from overreacting, but it may not eliminate flares entirely.
Other common triggers can still cause flares even while on adalimumab, including:
- Heat
- Stress
- Hormonal changes
- Friction
- Smoking
- Excess weight or obesity If you're noticing flares while on adalimumab, it's worth checking in with your dermatologist. They can help assess whether your current treatment plan needs adjusting or whether any triggers might be contributing to your flares.
2 days ago