That's a great question to bring to your doctor! Comparing GLP-1s and metformin specifically for HS symptom relief is tricky because there isn't strong head-to-head research on both for HS.
Here's what is known about GLP-1s and HS:
- Early small studies show GLP-1s (like semaglutide) may reduce HS flares and improve Show Full Answer
That's a great question to bring to your doctor! Comparing GLP-1s and metformin specifically for HS symptom relief is tricky because there isn't strong head-to-head research on both for HS.
Here's what is known about GLP-1s and HS:
- Early small studies show GLP-1s (like semaglutide) may reduce HS flares and improve quality of life
- In one study, flares dropped from every 8.5 weeks to every 12 weeks on semaglutide
- About 63% of myHSteam members surveyed reported GLP-1s helped reduce their HS symptoms
- Some members saw no HS improvement despite losing weight on GLP-1s GLP-1s are not yet a standard HS treatment, and results vary from person to person. HS is influenced by genetics, hormones, and environment, so what works for one person may not work for another.
Metformin is not currently covered in available HS research, so a direct comparison isn't possible here.
The best step is to speak with your dermatologist or healthcare provider about which option — or combination of treatments — makes the most sense for your specific situation.
August 10
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